Despite Tom Holland's Peter Parker previously fighting most of Spider-Man's major enemies, Marvel has plenty of characters to exploit in his MCU future.
Tom Holland's portrayal of the famed web slinger has already clashed with a large portion of the comic book character's villains.
However, the MCU should be able to discover new enemies for Peter. Due to Spider-Man: No Way Home's multiverse antics, the MCU has eliminated countless enemies for Holland to battle.
In Homecoming and Far from Home, Peter fought practically every enemy from the last two Spider-Man movies.
Marvel may run out of A-list Spider-Man villains. It will still have several choices if that happens.
Unlike the Green Goblin or Sandman, numerous lesser-known villains may make interesting live-action films.
Marvel introduced Doppelganger with Adam Warlock in Guardians of the Galaxy Vol. 3. In Marvel's Infinity War event, Adam Warlock's evil counterpart, the Magus,
created distorted copies of dozens of Marvel Comics characters, including Spider-Man. By the end of Infinity War, most of them died,